Understanding Peripheral Artery Disease

Peripheral Artery Disease (PAD) is a condition that occurs when the arteries that carry blood to the legs become narrowed or blocked. This reduced blood flow can make it harder for oxygen and nutrients to reach the muscles and tissues of the legs.

As circulation decreases, people may experience symptoms such as leg pain, cramping, fatigue while walking, or coldness in the lower legs or feet. In some cases, symptoms may develop gradually and become more noticeable during physical activity.

Understanding how peripheral artery disease affects circulation can help identify symptoms early and guide appropriate medical evaluation.

diagram showing peripheral artery disease with plaque causing reduced blood flow in leg arteries

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What Is Peripheral Artery Disease?

Peripheral artery disease occurs when fatty deposits build up inside the arteries that supply blood to the legs. This buildup, often called plaque, narrows the arteries and reduces blood flow.

Because the muscles and tissues in the legs rely on a steady supply of oxygen-rich blood, reduced circulation can lead to pain, fatigue, or other symptoms, particularly during walking or exercise.

Peripheral artery disease is a common vascular condition and may develop gradually over time.

Symptoms of Peripheral Artery Disease

Symptoms may vary depending on the severity of reduced blood flow.

Leg pain during walking or exercise
Cramping in the calf, thigh, or hip
Fatigue in the legs during activity
Coldness in the lower leg or foot
Numbness or weakness in the legs
Slower healing of wounds on the feet or legs
Shiny or smooth skin on the legs
Reduced hair growth on the legs

diagram showing plaque buildup in an artery causing peripheral artery disease

diagram showing normal artery vs artery with atherosclerotic plaque causing peripheral artery disease

Why Peripheral Artery Disease Happens

Peripheral artery disease develops when plaque builds up inside the arteries that carry blood to the legs. This process is known as atherosclerosis.

As plaque accumulates along the artery walls, the space inside the artery becomes narrower. This restricts blood flow and reduces the amount of oxygen reaching the muscles of the legs.

During physical activity, the muscles require more oxygen. When blood flow cannot meet that demand, symptoms such as pain or cramping may occur.

Risk Factors for Peripheral Artery Disease

Certain health conditions and lifestyle factors may increase the risk of developing peripheral artery disease.

Smoking
High blood pressure
High cholesterol
Diabetes
Aging
Family history of vascular disease
Obesity
Sedentary lifestyle

When Should You See a Specialist?

Symptoms such as leg pain during walking, persistent cold feet, or slow healing wounds on the legs may indicate circulation problems that should be evaluated. A specialist can assess blood flow in the arteries and determine whether peripheral artery disease may be present.

Early evaluation can help identify circulation problems and guide appropriate treatment.

Consider seeing a specialist if you experience:

leg pain during walking or exercise
cramping that improves with rest
cold feet or lower legs
numbness or weakness in the legs
slow healing wounds on the feet
changes in skin color on the legs
symptoms that worsen over time

vascular specialist evaluating patient during medical consultation

How Peripheral Artery Disease May Be Evaluated

A specialist may begin by reviewing symptoms and examining circulation in the legs and feet. In many cases, diagnostic tests may be used to measure blood flow and evaluate the condition of the arteries.

Tests such as ankle-brachial index (ABI) or vascular ultrasound may help determine whether reduced blood flow is present and how severe the blockage may be.

These evaluations help guide decisions about treatment and long-term management.

doctor performing vascular ultrasound to evaluate the leg

What Are You Experiencing?

These symptoms may sometimes appear alongside peripheral artery disease.

Concerned About Peripheral Artery Disease?

Learn more about circulation conditions and connect with specialists who evaluate and treat vascular problems affecting the legs and feet.

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Explore Symptoms

Understanding Peripheral Artery Disease

What Is Peripheral Artery Disease?

Symptoms of Peripheral Artery Disease

Why Peripheral Artery Disease Happens

Risk Factors for Peripheral Artery Disease

When Should You See a Specialist?

How Peripheral Artery Disease May Be Evaluated

What Are You Experiencing?

Leg Pain

Leg Cramps

Leg Swelling

Restless Legs

Leg Numbness / Tingling

Burning Sensation in Legs

Cold Feet

Heavy Legs

Concerned About Peripheral Artery Disease?

Understanding Peripheral Artery Disease

What Is Peripheral Artery Disease?

Symptoms of Peripheral Artery Disease

Why Peripheral Artery Disease Happens

Risk Factors for Peripheral Artery Disease

When Should You See a Specialist?

How Peripheral Artery Disease May Be Evaluated

What Are You Experiencing?

Concerned About Peripheral Artery Disease?

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